Tomorrow morning, at about 5:30am EST, I will be infected with Malaria. It's part of the
Vaccine Trial I volunteered for. You can read more about the study
here.
Friends have expressed concern. Family have evinced a growing leeriness about my presence.
First of all, it is nearly impossible for me to infect anyone else. Go read the
wiki article about Malaria, it's not "contagious" like a virus. I would have to be bitten by a mosquito of a particular breed, "the
definitive hosts for malaria parasites are female mosquitoes of the
Anopheles genus." It's not a mosquito that breeds in Maryland. So you can't get Malaria from me, and unless you show up with a jar full of non-native mosquitoes, I won't be a vector for your infection either.
I've also been asked about recurrence; Malaria never goes away, right?
Not the kind I will be exposed to; I am being bitten by mosquitoes that have the most serious type of malaria,
P. falciparum. That's serious and all, but it means I will not be at risk to suffer a recurrence; if I get it, they treat me, and it's done. Check it out;
Recurrent malaria
Malaria recurs after treatment for three reasons:
Recrudescence
occurs when parasites are not cleared by treatment (See the post-infection process below)
Reinfection
indicates complete clearance with new infection established from a
separate infective mosquito bite.
Relapse is specific to
P. vivax and
P. ovale and involves re-emergence of blood-stage parasites from latent parasites (hypnozoites) in the liver.
I'll get bit today. Malaria has an incubation of 7 to 21 days. Starting Tuesday July 17th, and for the following two weeks, I will be sleeping in the hospital. I can leave during the day, but if I start to exhibit any malaria symptoms, they'll keep me. They'll test me daily for Malaria, and once I test positive, they will treat me for it until I test negative twice in a row.
So I won't experience Recrudescence. I can't have a relapse.
It's a *little* worrisome, but seriously, life is a serious of calculated risks anyway. If this works, I did a little tiny bit to make the world tremendously safer. If it doesn't, *shrug* I'll be feverish for a few days and get paid very well for it.
And hey, free orange juice.